12 Best Southern Casserole Recipes

Chicken and Rice Casserole

A staple in Southern kitchens, this comforting casserole combines tender chicken with creamy rice for a satisfying meal.

Ingredients:

• 2 cups cooked chicken, shredded
• 1 cup long-grain white rice
• 2 cups chicken broth
• 1 can (10.5 oz) cream of mushroom soup
• 1 cup frozen mixed vegetables
• 1 cup shredded cheddar cheese
• 1 teaspoon garlic powder
• Salt and pepper to taste

Cooking method:

1. Preheat oven to 350°F (175°C).
2. In a large bowl, mix cooked chicken, rice, chicken broth, cream of mushroom soup, and frozen vegetables.
3. Pour the mixture into a greased baking dish and sprinkle with cheese, garlic powder, salt, and pepper.
4. Cover with foil and bake for 30 minutes, then remove foil and bake an additional 15 minutes until cheese is bubbly.

Southern Cornbread Casserole

This dish blends the delightful texture of cornbread with savory elements for a true Southern treat.

Ingredients:

• 1 package (8.5 oz) cornbread mix
• 1 can (15 oz) whole kernel corn, drained
• 1 can (15 oz) creamed corn
• 1 cup sour cream
• 1/2 cup melted butter
• 1 cup shredded cheddar cheese

Cooking method:

1. Preheat oven to 350°F (175°C).
2. In a large bowl, combine cornbread mix, whole kernel corn, creamed corn, sour cream, and melted butter.
3. Pour the mixture into a greased baking dish and sprinkle the top with cheese.
4. Bake for 45 minutes or until the top is golden brown and set.

Shrimp and Grits Casserole

This casserole takes the classic Southern dish, shrimp and grits, and transforms it into a delightful baked version.

Ingredients:

• 1 lb shrimp, peeled and deveined
• 2 cups cooked grits
• 1 cup sharp cheddar cheese, grated
• 1/2 cup bacon, cooked and crumbled
• 1/4 cup scallions, chopped
• 1 teaspoon Cajun seasoning

Cooking method:

1. Preheat oven to 375°F (190°C).
2. Layer cooked grits in a greased baking dish, sprinkle with cheese, bacon, and scallions.
3. Toss shrimp with Cajun seasoning and layer over the grits.
4. Bake for 20-25 minutes or until shrimp are cooked through.

Southern Green Bean Casserole

This version of the classic green bean casserole is a must-have at any Southern gathering.

Ingredients:

• 2 cans (14.5 oz each) green beans, drained
• 1 can (10.5 oz) cream of mushroom soup
• 1/2 cup milk
• 1 cup fried onions
• 1 teaspoon soy sauce
• Salt and pepper to taste

Cooking method:

1. Preheat oven to 350°F (175°C).
2. In a bowl, mix green beans, cream of mushroom soup, milk, soy sauce, salt, and pepper.
3. Pour into a greased baking dish and top with fried onions.
4. Bake for 25 minutes or until bubbly and onions are golden brown.

Southern Squash Casserole

This cheesy baked squash casserole is a crowd-pleaser at any Southern table.

Ingredients:

• 3 cups sliced yellow squash
• 1/2 cup chopped onion
• 1 cup shredded cheddar cheese
• 1/2 cup sour cream
• 1/4 cup mayonnaise
• 1 cup crushed crackers
• Salt and pepper to taste

Cooking method:

1. Preheat oven to 350°F (175°C).
2. Boil squash and onion in salted water until tender, drain well.
3. In a bowl, combine squash mixture, cheese, sour cream, mayonnaise, salt, and pepper, then place in a greased baking dish.
4. Top with crushed crackers and bake for 30 minutes or until golden.

Southern Pimento Cheese Casserole

Transform classic pimento cheese into a hearty casserole with this simple recipe.

Ingredients:

• 2 cups elbow macaroni, cooked
• 1 cup pimento cheese spread
• 1 cup cheddar cheese, shredded
• 1/2 cup milk
• 1/4 teaspoon paprika
• 1/4 teaspoon black pepper

Cooking method:

1. Preheat oven to 350°F (175°C).
2. Combine cooked macaroni, pimento cheese, cheddar cheese, milk, paprika, and black pepper.
3. Transfer to a greased baking dish.
4. Bake for 20-25 minutes until bubbly and lightly golden.

Southern Sausage and Biscuit Casserole

A hearty and comforting dish, combining the flavors of sausage and biscuit in one satisfying casserole.

Ingredients:

• 1 lb breakfast sausage
• 1 can (16.3 oz) refrigerated biscuit dough
• 4 large eggs
• 1 cup milk
• 1 cup shredded cheddar cheese
• Salt and pepper to taste

Cooking method:

1. Preheat oven to 350°F (175°C).
2. Brown sausage in a skillet; drain excess fat.
3. Cut biscuit dough into quarters and layer in a greased baking dish.
4. Whisk eggs and milk, pour over biscuits, top with sausage and cheese.
5. Bake for 30-35 minutes until golden brown and set.

Southern Sweet Potato Casserole

A classic holiday dish, this sweet potato casserole features a crunchy pecan topping.

Ingredients:

• 4 cups mashed sweet potatoes
• 1 cup brown sugar
• 1/2 cup melted butter
• 2 large eggs, beaten
• 1 teaspoon vanilla extract
• 1 cup chopped pecans
• 1/2 cup all-purpose flour

Cooking method:

1. Preheat oven to 350°F (175°C).
2. Mix sweet potatoes, brown sugar, melted butter, eggs, and vanilla, then spread in a greased baking dish.
3. Combine pecans, flour, and remaining brown sugar, sprinkle over sweet potato mixture.
4. Bake for 25-30 minutes until topping is crisp and golden.

Southern Black-Eyed Pea Casserole

Hearty and nourishing, this casserole is packed with flavor and perfect for New Year's luck.

Ingredients:

• 2 cans (15 oz each) black-eyed peas, drained
• 1 cup cooked rice
• 1/2 cup diced tomatoes
• 1/2 cup chopped green bell pepper
• 1 cup shredded cheddar cheese
• 1 teaspoon hot sauce
• Salt and pepper to taste

Cooking method:

1. Preheat oven to 350°F (175°C).
2. In a large bowl, combine black-eyed peas, rice, tomatoes, bell pepper, cheese, hot sauce, salt, and pepper.
3. Transfer mixture to a greased baking dish.
4. Bake for 25-30 minutes until heated through and cheese is melted.

Southern Banana Pudding Casserole

A unique twist on the classic banana pudding, this casserole is creamy and delightful.

Ingredients:

• 4 bananas, sliced
• 1 package (5 oz) instant vanilla pudding mix
• 3 cups cold milk
• 1/2 cup sour cream
• 1 package (12 oz) vanilla wafers
• 1 cup whipped topping

Cooking method:

1. In a bowl, whisk pudding mix, milk, and sour cream until smooth.
2. In a greased baking dish, layer half of the vanilla wafers, bananas, and pudding mixture; repeat.
3. Top with whipped topping and refrigerate for at least 2 hours before serving.